IL-10 modified mRNA monotherapy prolongs survival after composite facial allografting through the induction of mixed chimerism

Vascularized composite allotransplantation has great potential in face transplantation by supporting functional restoration following tissue grafting. However, the need for lifelong administration of immunosuppressive drugs still limits its wide use. Modified mRNA (modRNA) technology provides an eff...

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Detalles Bibliográficos
Autores principales: Aviña, Ana Elena, De Paz, Dante, Huang, Shu-Chun, Chen, Kuan-Hung, Chang, Yun-Ching, Lee, Chin-Ming, Lin, Chia-Hsien, Wei, Fu-Chan, Wang, Aline Yen Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996371/
https://www.ncbi.nlm.nih.gov/pubmed/36910717
http://dx.doi.org/10.1016/j.omtn.2023.02.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996371/
https://www.ncbi.nlm.nih.gov/pubmed/36910717
http://dx.doi.org/10.1016/j.omtn.2023.02.016

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