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Tracking the progeny of adoptively transferred virus-specific T cells in patients posttransplant using TCR sequencing

Adoptive cellular therapies with T cells are increasingly used to treat a variety of conditions. For instance, in a recent phase 1/2 trial, we prophylactically administered multivirus-specific T-cell products to protect recipients of T-cell–depleted allogeneic stem cell grafts against viral reactiva...

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Detalles Bibliográficos
Autores principales: Huisman, W., Roex, M. C. J., Hageman, L., Koster, E. A. S., Veld, S. A. J., Hoogstraten, C., van Balen, P., van Egmond, H. M., van Bergen, C. A. M., Einsele, H., Germeroth, L., Amsen, D., Falkenburg, J. H. F., Jedema, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996373/
https://www.ncbi.nlm.nih.gov/pubmed/36121440
http://dx.doi.org/10.1182/bloodadvances.2022007270