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Discrepancy between Mtb-specific IFN-γ and IgG responses in HIV-positive people with low CD4 counts

BACKGROUND: Tuberculosis (TB) is a leading infectious cause of death worldwide and treating latent TB infection (LTBI) with TB preventative therapy is a global priority. This study aimed to measure interferon gamma (IFN-γ) release assay (IGRA) positivity (the current reference standard for LTBI diag...

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Detalles Bibliográficos
Autores principales: Mthembu, Maphe, Bowman, Kathryn A., Davies, Leela R.L., Khuzwayo, Sharon, Mazibuko, Lusanda, Bassett, Thierry, Ramjit, Dirhona, Mhlane, Zoey, Karim, Farina, Alter, Galit, Ndung'u, Thumbi, Wong, Emily B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996381/
https://www.ncbi.nlm.nih.gov/pubmed/36870197
http://dx.doi.org/10.1016/j.ebiom.2023.104504