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In-vial solid-phase extraction of polycyclic aromatic hydrocarbons in drug formulations stored in packaging containing rubber

Polycyclic aromatic hydrocarbons (PAHs) are a class of ubiquitous and persistent organic compounds that are significantly teratogenic, carcinogenic and mutagenic. Rubber stoppers commonly used in sterile formulation packaging materials often contain carbon black as the additive to enhance mechanical...

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Detalles Bibliográficos
Autores principales: Yang, Hao, Ding, Yinmeng, Ding, Ya, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996413/
https://www.ncbi.nlm.nih.gov/pubmed/36909765
http://dx.doi.org/10.1039/d2ra07582b