Circadian clock molecule REV-ERBα regulates lung fibrotic progression through collagen stabilization

Molecular clock REV-ERBα is central to regulating lung injuries, and decreased REV-ERBα abundance mediates sensitivity to pro-fibrotic insults and exacerbates fibrotic progression. In this study, we determine the role of REV-ERBα in fibrogenesis induced by bleomycin and Influenza A virus (IAV). Bleo...

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Detalles Bibliográficos
Autores principales: Wang, Qixin, Sundar, Isaac Kirubakaran, Lucas, Joseph H., Park, Jun-Gyu, Nogales, Aitor, Martinez-Sobrido, Luis, Rahman, Irfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996598/
https://www.ncbi.nlm.nih.gov/pubmed/36894533
http://dx.doi.org/10.1038/s41467-023-36896-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996598/
https://www.ncbi.nlm.nih.gov/pubmed/36894533
http://dx.doi.org/10.1038/s41467-023-36896-0

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