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Hippocampal vulnerability to hyperhomocysteinemia worsens pathological outcomes of mild traumatic brain injury in rats

BACKGROUND: Mild traumatic brain injury (mTBI) generally resolves within weeks. However, 15-30% of patients present persistent pathological and neurobehavioral sequelae that negatively affect their quality of life. Hyperhomocysteinemia (HHCY) is a neurotoxic condition derived from homocysteine accum...

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Detalles Bibliográficos
Autores principales: Tchantchou, Flaubert, Hsia, Ru-ching, Puche, Adam, Fiskum, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996738/
https://www.ncbi.nlm.nih.gov/pubmed/36909831
http://dx.doi.org/10.1177/11795735231160025