Pyrazolones Potentiate Colistin Activity against MCR-1-Producing Resistant Bacteria: Computational and Microbiological Study

[Image: see text] The polymyxin colistin is a last line antibiotic for extensively resistant Gram-negative bacteria. Colistin binding to lipid A disrupts the Gram-negative outer membrane, but mobile colistin resistance (mcr) gene family members confer resistance by catalyzing phosphoethanolamine (PE...

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Detalles Bibliográficos
Autores principales: Hanpaibool, Chonnikan, Ngamwongsatit, Natharin, Ounjai, Puey, Yotphan, Sirilata, Wolschann, Peter, Mulholland, Adrian J., Spencer, James, Rungrotmongkol, Thanyada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996792/
https://www.ncbi.nlm.nih.gov/pubmed/36910942
http://dx.doi.org/10.1021/acsomega.2c07165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996792/
https://www.ncbi.nlm.nih.gov/pubmed/36910942
http://dx.doi.org/10.1021/acsomega.2c07165

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