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Investigating the Orientation of an Interfacially Adsorbed Monoclonal Antibody and Its Fragments Using Neutron Reflection
[Image: see text] Interfacial adsorption is a molecular process occurring during the production, purification, transport, and storage of antibodies, with a direct impact on their structural stability and subsequent implications on their bioactivities. While the average conformational orientation of...
Autores principales: | Ruane, Sean, Li, Zongyi, Hollowell, Peter, Hughes, Arwel, Warwicker, Jim, Webster, John R. P., van der Walle, Christopher F., Kalonia, Cavan, Lu, Jian R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996827/ https://www.ncbi.nlm.nih.gov/pubmed/36795985 http://dx.doi.org/10.1021/acs.molpharmaceut.2c00864 |
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