Neurofibromatosis type 1-dependent alterations in mouse microglia function are not cell-intrinsic

We previously discovered a sex-by-genotype defect in microglia function using a heterozygous germline knockout mouse model of Neurofibromatosis type 1 (Nf1 ± mice), in which only microglia from male Nf1 ± mice exhibited defects in purinergic signaling. Herein, we leveraged an unbiased proteomic appr...

Descripción completa

Detalles Bibliográficos
Autores principales: Logiacco, Francesca, Grzegorzek, Laura Cathleen, Cordell, Elizabeth C., Popp, Oliver, Mertins, Philipp, Gutmann, David H., Kettenmann, Helmut, Semtner, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996880/
https://www.ncbi.nlm.nih.gov/pubmed/36890585
http://dx.doi.org/10.1186/s40478-023-01525-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996880/
https://www.ncbi.nlm.nih.gov/pubmed/36890585
http://dx.doi.org/10.1186/s40478-023-01525-w

Ejemplares similares