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PCGF6/MAX/KDM5D facilitates MAZ/CDK4 axis expression and pRCC progression by hypomethylation of the DNA promoter

Polycomb group RING finger protein 6 (PCGF6) plays an important role as a regulator of transcription in a variety of cellular processes, including tumorigenesis. However, the function and expression of PCGF6 in papillary RCC (pRCC) remain unclear. In the present study, we found that PCGF6 expression...

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Detalles Bibliográficos
Autores principales: Zhu, Meng, Zhang, Ruo-Nan, Zhang, Hong, Qu, Chang-bao, Zhang, Xiao-chong, Ren, Li-Xin, Yang, Zhan, Gu, Jun-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996882/
https://www.ncbi.nlm.nih.gov/pubmed/36890610
http://dx.doi.org/10.1186/s13072-023-00483-w