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Characterisation of tumor microenvironment and prevalence of CD274/PD-L1 genetic alterations difference in colorectal Cancer

BACKGROUND: Large-scale genomic alterations, especially CD274/PD-L1 gene amplification, have great impact on anti-PD-1 efficacy on cancers such as Hodgkin’s lymphoma. However, the prevalence of PD-L1 genetic alterations in colorectal cancer (CRC) and its correlation with the tumor immune microenviro...

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Detalles Bibliográficos
Autores principales: Yang, Lin, Liu, Shousheng, He, Wenzhuo, Xiong, Zhenchong, Xia, Liangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996909/
https://www.ncbi.nlm.nih.gov/pubmed/36894899
http://dx.doi.org/10.1186/s12885-023-10610-1