Piperine improves the sensitivity of osteosarcoma cells to doxorubicin by inducing apoptosis and inhibiting the PI3K/AKT/GSK-3β pathway

BACKGROUND: Osteosarcoma is a primary bone malignancy associated with the highest incidence rate. Chemotherapy for osteosarcoma has not substantially changed, and survival of patients with metastatic tumours has reached a plateau. Doxorubicin (DOX) is a broad-spectrum anti-osteosarcoma drug; however...

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Detalles Bibliográficos
Autores principales: Qi, Yubin, Yao, Lin, Liu, Jianke, Wang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996932/
https://www.ncbi.nlm.nih.gov/pubmed/36895009
http://dx.doi.org/10.1186/s13018-023-03642-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996932/
https://www.ncbi.nlm.nih.gov/pubmed/36895009
http://dx.doi.org/10.1186/s13018-023-03642-7

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