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B7-H3 expression is associated with high PD-L1 expression in clear cell renal cell carcinoma and predicts poor prognosis

BACKGROUND: Clear cell Renal cell carcinoma (ccRCC) is an immunogenic tumor. B7 family members, such as CTLA-4, PD-1, and PD-L1, are the main components of immune checkpoints that regulate various immune responses. Specifically, B7-H3 regulates T cell-mediated immune responses against cancer. This s...

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Detalles Bibliográficos
Autores principales: Lee, Jung Hee, Kim, Yong Jun, Ryu, Hyun Woo, Shin, Seung Won, Kim, Eun Ji, Shin, So Hyun, Park, Joon Young, Kim, So Young, Hwang, Chung Su, Na, Joo-Young, Shin, Dong Hoon, Kim, Jee Yeon, Lee, Hyun Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9996938/
https://www.ncbi.nlm.nih.gov/pubmed/36894965
http://dx.doi.org/10.1186/s13000-023-01320-0