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Toward “CO in a Pill”: Silica-Immobilized Organic CO Prodrugs for Studying the Feasibility of Systemic Delivery of CO via In Situ Gastrointestinal CO Release

[Image: see text] Carbon monoxide (CO), an endogenous signaling molecule, is known to exert a range of pharmacological effects, including anti-inflammation, organ protection, and antimetastasis in various animal models. We have previously shown the ability of organic prodrugs to deliver CO systemica...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoxiao, Tripathi, Ravi, Wang, Minjia, Lu, Wen, Anifowose, Abiodun, Tan, Chalet, Wang, Binghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997063/
https://www.ncbi.nlm.nih.gov/pubmed/36802675
http://dx.doi.org/10.1021/acs.molpharmaceut.2c01104