Glial cell transcriptome analyses in 3xTg-AD mice: Effects of aging, disease progression, and anti-Aβ immunotherapy

BACKGROUND: To investigate how changes in expression of glial genes relate to a progression of Alzheimer’s disease (AD) pathology, and how anti-Aβ immunotherapy impact these changes, we conducted a transcriptomic analysis for brains from cohorts of 2-, 10-, and 20 month old 3xTg-AD mice, and a cross...

Descripción completa

Detalles Bibliográficos
Autores principales: Lambracht-Washington, Doris, Fu, Min, Manouchehri, Navid, Hynan, Linda S., Stuve, Olaf, Rosenberg, Roger N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997156/
https://www.ncbi.nlm.nih.gov/pubmed/36911262
http://dx.doi.org/10.1016/j.nbas.2023.100066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997156/
https://www.ncbi.nlm.nih.gov/pubmed/36911262
http://dx.doi.org/10.1016/j.nbas.2023.100066

Ejemplares similares