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Aging entails distinct requirements for Rb at maintaining adult neurogenesis

Cell cycle proteins play essential roles in regulating embryonic and adult neurogenesis in the mammalian brain. A key example is the Retinoblastoma protein (Rb) whose loss disrupts the whole neurogenic program during brain development, but only results in increased progenitor proliferation in the ad...

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Detalles Bibliográficos
Autores principales: Omais, Saad, Hilal, Rouba N., Halaby, Nour N., Jaafar, Carine, Ghanem, Noël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997174/
https://www.ncbi.nlm.nih.gov/pubmed/36908894
http://dx.doi.org/10.1016/j.nbas.2022.100041