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Early memory deficits and extensive brain network disorganization in the App(NL-F)/MAPT double knock-in mouse model of familial Alzheimer’s disease

A critical challenge in current research on Alzheimer’s disease (AD) is to clarify the relationship between network dysfunction and the emergence of subtle memory deficits in itspreclinical stage. The AppNL-F/MAPT double knock-in (dKI) model with humanized β-amyloid peptide (Aβ) and tau was used to...

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Detalles Bibliográficos
Autores principales:	Borcuk, Christopher, Héraud, Céline, Herbeaux, Karine, Diringer, Margot, Panzer, Élodie, Scuto, Jil, Hashimoto, Shoko, Saido, Takaomi C., Saito, Takashi, Goutagny, Romain, Battaglia, Demian, Mathis, Chantal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997176/ https://www.ncbi.nlm.nih.gov/pubmed/36908877 http://dx.doi.org/10.1016/j.nbas.2022.100042

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