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TLR4 signaling modulates extracellular matrix production in the lamina cribrosa

The optic nerve head (ONH) is a place of vulnerability during glaucoma progression due to increased intraocular pressure damaging the retinal ganglion cell axons. The molecular signaling pathways involved in generating glaucomatous ONH damage has not been fully elucidated. There is a great deal of e...

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Detalles Bibliográficos
Autores principales: Geiduschek, Emma K., Milne, Paige D., Mzyk, Philip, Mavlyutov, Timur A., McDowell, Colleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997209/
https://www.ncbi.nlm.nih.gov/pubmed/36911656
http://dx.doi.org/10.3389/fopht.2022.968381