Size- and Stereochemistry-Dependent Transcriptional Bypass of DNA Alkyl Phosphotriester Adducts in Mammalian Cells

Environmental, endogenous and therapeutic alkylating agents can react with internucleotide phosphate groups in DNA to yield alkyl phosphotriester (PTE) adducts. Alkyl-PTEs are induced at relatively high frequencies and are persistent in mammalian tissues; however, their biological consequences in ma...

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Detalles Bibliográficos
Autores principales: Tan, Ying, Wu, Jiabin, Clabaugh, Garrit, Li, Lin, Du, Hua, Wang, Yinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997456/
https://www.ncbi.nlm.nih.gov/pubmed/36911626
http://dx.doi.org/10.3390/dna2040016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997456/
https://www.ncbi.nlm.nih.gov/pubmed/36911626
http://dx.doi.org/10.3390/dna2040016

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