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Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice

Age-associated B cells (ABCs) are formed under inflammatory conditions and are considered a type of memory B cell (MBC) expressing the transcription factor T-bet. In SLE, ABC frequency is correlated with disease, and they are thought to be the source of autoantibody-secreting cells. However, in infl...

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Detalles Bibliográficos
Autores principales: Nickerson, Kevin M., Smita, Shuchi, Hoehn, Kenneth B., Marinov, Anthony D., Thomas, Kayla B., Kos, Justin T., Yang, Yi, Bastacky, Sheldon I., Watson, Corey T., Kleinstein, Steven H., Shlomchik, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997508/
https://www.ncbi.nlm.nih.gov/pubmed/36828389
http://dx.doi.org/10.1084/jem.20221346