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The rate of spontaneous mutations in yeast deficient for MutSβ function

Mutations in simple sequence repeat loci underlie many inherited disorders in humans, and are increasingly recognized as important determinants of natural phenotypic variation. In eukaryotes, mutations in these sequences are primarily repaired by the MutSβ mismatch repair complex. To better understa...

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Detalles Bibliográficos
Autores principales: Plavskin, Yevgeniy, de Biase, Maria Stella, Schwarz, Roland F, Siegal, Mark L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997558/
https://www.ncbi.nlm.nih.gov/pubmed/36529906
http://dx.doi.org/10.1093/g3journal/jkac330