VALPROIC ACID INHIBITS CLASSICAL MONOCYTE-DERIVED TISSUE FACTOR AND ALLEVIATES HEMORRHAGIC SHOCK-INDUCED ACUTE LUNG INJURY IN RATS

Background: Monocytes and monocyte-derived tissue factor (TF) promote the development of sepsis-induced acute lung injury (ALI). Classical monocytes (C-Mcs) can be induced to express TF. Valproic acid (VPA) alleviates hemorrhagic shock (HS)–induced ALI (HS/ALI) and inhibits TF expression in monocyte...

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Detalles Bibliográficos
Autores principales: Shao, Lina, Wu, Bing, Liu, Chang, Chong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Basic Science Aspects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997640/
https://www.ncbi.nlm.nih.gov/pubmed/36443067
http://dx.doi.org/10.1097/SHK.0000000000002064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997640/
https://www.ncbi.nlm.nih.gov/pubmed/36443067
http://dx.doi.org/10.1097/SHK.0000000000002064

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