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VALPROIC ACID INHIBITS CLASSICAL MONOCYTE-DERIVED TISSUE FACTOR AND ALLEVIATES HEMORRHAGIC SHOCK-INDUCED ACUTE LUNG INJURY IN RATS

Background: Monocytes and monocyte-derived tissue factor (TF) promote the development of sepsis-induced acute lung injury (ALI). Classical monocytes (C-Mcs) can be induced to express TF. Valproic acid (VPA) alleviates hemorrhagic shock (HS)–induced ALI (HS/ALI) and inhibits TF expression in monocyte...

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Detalles Bibliográficos
Autores principales:	Shao, Lina, Wu, Bing, Liu, Chang, Chong, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Basic Science Aspects
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997640/ https://www.ncbi.nlm.nih.gov/pubmed/36443067 http://dx.doi.org/10.1097/SHK.0000000000002064

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