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Trained hypertensive rats exhibit decreased transcellular vesicle trafficking, increased tight junctions’ density, restored blood-brain barrier permeability and normalized autonomic control of the circulation

Introduction: Chronic hypertension is accompanied by either blood-brain barrier (BBB) leakage and autonomic dysfunction. There is no consensus on the mechanism determining increased BBB permeability within autonomic areas. While some reports suggested tight junction’s breakdown, others indicated the...

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Detalles Bibliográficos
Autores principales: Candido, Vanessa B., Perego, Sany M., Ceroni, Alexandre, Metzger, Martin, Colquhoun, Alison, Michelini, Lisete C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997677/
https://www.ncbi.nlm.nih.gov/pubmed/36909225
http://dx.doi.org/10.3389/fphys.2023.1069485