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The alphavirus nonstructural protein 2 NTPase induces a host translational shut-off through phosphorylation of eEF2 via cAMP-PKA-eEF2K signaling
Chikungunya virus (CHIKV) is a reemerging alphavirus. Since 2005, it has infected millions of people during outbreaks in Africa, Asia, and South/Central America. CHIKV replication depends on host cell factors at many levels and is expected to have a profound effect on cellular physiology. To obtain...
Autores principales: | Treffers, Emmely E., Tas, Ali, Scholte, Florine E. M., de Ru, Arnoud H., Snijder, Eric J., van Veelen, Peter A., van Hemert, Martijn J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997916/ https://www.ncbi.nlm.nih.gov/pubmed/36848386 http://dx.doi.org/10.1371/journal.ppat.1011179 |
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