The alphavirus nonstructural protein 2 NTPase induces a host translational shut-off through phosphorylation of eEF2 via cAMP-PKA-eEF2K signaling

Chikungunya virus (CHIKV) is a reemerging alphavirus. Since 2005, it has infected millions of people during outbreaks in Africa, Asia, and South/Central America. CHIKV replication depends on host cell factors at many levels and is expected to have a profound effect on cellular physiology. To obtain...

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Detalles Bibliográficos
Autores principales: Treffers, Emmely E., Tas, Ali, Scholte, Florine E. M., de Ru, Arnoud H., Snijder, Eric J., van Veelen, Peter A., van Hemert, Martijn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997916/
https://www.ncbi.nlm.nih.gov/pubmed/36848386
http://dx.doi.org/10.1371/journal.ppat.1011179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997916/
https://www.ncbi.nlm.nih.gov/pubmed/36848386
http://dx.doi.org/10.1371/journal.ppat.1011179

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