Allelic contribution of Nrxn1α to autism-relevant behavioral phenotypes in mice

Copy number variations (CNVs) in the Neurexin 1 (NRXN1) gene, which encodes a presynaptic protein involved in neurotransmitter release, are some of the most frequently observed single-gene variants associated with autism spectrum disorder (ASD). To address the functional contribution of NRXN1 CNVs t...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Bing, Ho, Yugong, Fasolino, Maria, Medina, Joanna, O’Brien, William Timothy, Lamonica, Janine M., Nugent, Erin, Brodkin, Edward S., Fuccillo, Marc V., Bucan, Maja, Zhou, Zhaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997995/
https://www.ncbi.nlm.nih.gov/pubmed/36848371
http://dx.doi.org/10.1371/journal.pgen.1010659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9997995/
https://www.ncbi.nlm.nih.gov/pubmed/36848371
http://dx.doi.org/10.1371/journal.pgen.1010659

Ejemplares similares