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Lack of adipocyte IP3R1 reduces diet-induced obesity and greatly improves whole-body glucose homeostasis

The normal function of skeletal muscle and adipose tissue ensures whole-body glucose homeostasis. Ca(2+) release channel inositol 1,4,5-trisphosphate receptor 1 (IP3R1) plays a vital role in regulating diet-induced obesity and disorders, but its functions in peripheral tissue regulating glucose home...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Wang, Lu, Wang, Yubo, He, Linjuan, Xu, Doudou, Yan, Enfa, Guo, Jianxin, Ma, Chenghong, Zhang, Pengguang, Yin, Jingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998023/
https://www.ncbi.nlm.nih.gov/pubmed/36894534
http://dx.doi.org/10.1038/s41420-023-01389-y