Smooth muscle α(v) integrins regulate vascular fibrosis via CD109 downregulation of TGF-β signalling

AIMS: α(v) integrins are implicated in fibrosis in a number of organs through their ability to activate TGF-β. However their role in vascular fibrosis and collagen accumulation is only partially understood. Here we have used α(v) conditional knockout mice and cell lines to determine how α(v) contrib...

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Detalles Bibliográficos
Autores principales: Li, Zhenlin, Belozertseva, Ekaterina, Parlakian, Ara, Bascetin, Rümeyza, Louis, Huguette, Kawamura, Yuki, Blanc, Jocelyne, Gao-Li, Jacqueline, Pinet, Florence, Lacy-Hulbert, Adam, Challande, Pascal, Humphrey, Jay D, Regnault, Veronique, Lacolley, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998030/
https://www.ncbi.nlm.nih.gov/pubmed/36909248
http://dx.doi.org/10.1093/ehjopen/oead010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998030/
https://www.ncbi.nlm.nih.gov/pubmed/36909248
http://dx.doi.org/10.1093/ehjopen/oead010

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