Exploiting the mediating role of the metabolome to unravel transcript-to-phenotype associations

Despite the success of genome-wide association studies (GWASs) in identifying genetic variants associated with complex traits, understanding the mechanisms behind these statistical associations remains challenging. Several methods that integrate methylation, gene expression, and protein quantitative...

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Detalles Bibliográficos
Autores principales: Auwerx, Chiara, Sadler, Marie C, Woh, Tristan, Reymond, Alexandre, Kutalik, Zoltán, Porcu, Eleonora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998083/
https://www.ncbi.nlm.nih.gov/pubmed/36891970
http://dx.doi.org/10.7554/eLife.81097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998083/
https://www.ncbi.nlm.nih.gov/pubmed/36891970
http://dx.doi.org/10.7554/eLife.81097

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