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Single cell preparations of Mycobacterium tuberculosis damage the mycobacterial envelope and disrupt macrophage interactions

For decades, investigators have studied the interaction of Mycobacterium tuberculosis (Mtb) with macrophages, which serve as a major cellular niche for the bacilli. Because Mtb are prone to aggregation, investigators rely on varied methods to disaggregate the bacteria for these studies. Here, we exa...

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Detalles Bibliográficos
Autores principales: Mittal, Ekansh, Roth, Andrew T, Seth, Anushree, Singamaneni, Srikanth, Beatty, Wandy, Philips, Jennifer A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998084/
https://www.ncbi.nlm.nih.gov/pubmed/36852737
http://dx.doi.org/10.7554/eLife.85416