eRNA profiling uncovers the enhancer landscape of oesophageal adenocarcinoma and reveals new deregulated pathways

Cancer is driven by both genetic and epigenetic changes that impact on gene expression profiles and the resulting tumourigenic phenotype. Enhancers are transcriptional regulatory elements that are key to our understanding of how this rewiring of gene expression is achieved in cancer cells. Here, we...

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Detalles Bibliográficos
Autores principales: Ahmed, Ibrahim, Yang, Shen-Hsi, Ogden, Samuel, Zhang, Wei, Li, Yaoyong, Sharrocks, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998086/
https://www.ncbi.nlm.nih.gov/pubmed/36803948
http://dx.doi.org/10.7554/eLife.80840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998086/
https://www.ncbi.nlm.nih.gov/pubmed/36803948
http://dx.doi.org/10.7554/eLife.80840

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