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eRNA profiling uncovers the enhancer landscape of oesophageal adenocarcinoma and reveals new deregulated pathways
Cancer is driven by both genetic and epigenetic changes that impact on gene expression profiles and the resulting tumourigenic phenotype. Enhancers are transcriptional regulatory elements that are key to our understanding of how this rewiring of gene expression is achieved in cancer cells. Here, we...
Autores principales: | Ahmed, Ibrahim, Yang, Shen-Hsi, Ogden, Samuel, Zhang, Wei, Li, Yaoyong, Sharrocks, Andrew D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998086/ https://www.ncbi.nlm.nih.gov/pubmed/36803948 http://dx.doi.org/10.7554/eLife.80840 |
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