Interplay of adherens junctions and matrix proteolysis determines the invasive pattern and growth of squamous cell carcinoma

Cancers, such as squamous cell carcinoma, frequently invade as multicellular units. However, these invading units can be organised in a variety of ways, ranging from thin discontinuous strands to thick ‘pushing’ collectives. Here we employ an integrated experimental and computational approach to ide...

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Detalles Bibliográficos
Autores principales: Kato, Takuya, Jenkins, Robert P, Derzsi, Stefanie, Tozluoglu, Melda, Rullan, Antonio, Hooper, Steven, Chaleil, Raphaël AG, Joyce, Holly, Fu, Xiao, Thavaraj, Selvam, Bates, Paul A, Sahai, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998089/
https://www.ncbi.nlm.nih.gov/pubmed/36892272
http://dx.doi.org/10.7554/eLife.76520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998089/
https://www.ncbi.nlm.nih.gov/pubmed/36892272
http://dx.doi.org/10.7554/eLife.76520

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