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Interplay of adherens junctions and matrix proteolysis determines the invasive pattern and growth of squamous cell carcinoma
Cancers, such as squamous cell carcinoma, frequently invade as multicellular units. However, these invading units can be organised in a variety of ways, ranging from thin discontinuous strands to thick ‘pushing’ collectives. Here we employ an integrated experimental and computational approach to ide...
Autores principales: | Kato, Takuya, Jenkins, Robert P, Derzsi, Stefanie, Tozluoglu, Melda, Rullan, Antonio, Hooper, Steven, Chaleil, Raphaël AG, Joyce, Holly, Fu, Xiao, Thavaraj, Selvam, Bates, Paul A, Sahai, Erik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998089/ https://www.ncbi.nlm.nih.gov/pubmed/36892272 http://dx.doi.org/10.7554/eLife.76520 |
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