Orai3 and Orai1 mediate CRAC channel function and metabolic reprogramming in B cells

The essential role of store-operated Ca(2+) entry (SOCE) through Ca(2+) release-activated Ca(2+) (CRAC) channels in T cells is well established. In contrast, the contribution of individual Orai isoforms to SOCE and their downstream signaling functions in B cells are poorly understood. Here, we demon...

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Detalles Bibliográficos
Autores principales: Emrich, Scott M, Yoast, Ryan E, Zhang, Xuexin, Fike, Adam J, Wang, Yin-Hu, Bricker, Kristen N, Tao, Anthony Y, Xin, Ping, Walter, Vonn, Johnson, Martin T, Pathak, Trayambak, Straub, Adam C, Feske, Stefan, Rahman, Ziaur SM, Trebak, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998091/
https://www.ncbi.nlm.nih.gov/pubmed/36803766
http://dx.doi.org/10.7554/eLife.84708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998091/
https://www.ncbi.nlm.nih.gov/pubmed/36803766
http://dx.doi.org/10.7554/eLife.84708

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