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Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis

Centrosomes are orbited by centriolar satellites, dynamic multiprotein assemblies nucleated by Pericentriolar material 1 (PCM1). To study the requirement for centriolar satellites, we generated mice lacking PCM1, a crucial component of satellites. Pcm1(−/−) mice display partially penetrant perinatal...

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Detalles Bibliográficos
Autores principales: Hall, Emma A, Kumar, Dhivya, Prosser, Suzanna L, Yeyati, Patricia L, Herranz-Pérez, Vicente, García-Verdugo, Jose Manuel, Rose, Lorraine, McKie, Lisa, Dodd, Daniel O, Tennant, Peter A, Megaw, Roly, Murphy, Laura C, Ferreira, Marisa F, Grimes, Graeme, Williams, Lucy, Quidwai, Tooba, Pelletier, Laurence, Reiter, Jeremy F, Mill, Pleasantine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998092/
https://www.ncbi.nlm.nih.gov/pubmed/36790165
http://dx.doi.org/10.7554/eLife.79299