Pregabalin Silences Oxaliplatin-Activated Sensory Neurons to Relieve Cold Allodynia

Oxaliplatin is a platinum-based chemotherapeutic agent that causes cold and mechanical allodynia in up to 90% of patients. Silent Nav1.8-positive nociceptive cold sensors have been shown to be unmasked by oxaliplatin, and this event has been causally linked to the development of cold allodynia. We e...

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Detalles Bibliográficos
Autores principales: Iseppon, Federico, Luiz, Ana P., Linley, John E., Wood, John N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998121/
https://www.ncbi.nlm.nih.gov/pubmed/36720644
http://dx.doi.org/10.1523/ENEURO.0395-22.2022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998121/
https://www.ncbi.nlm.nih.gov/pubmed/36720644
http://dx.doi.org/10.1523/ENEURO.0395-22.2022

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