Cargando…
Pregabalin Silences Oxaliplatin-Activated Sensory Neurons to Relieve Cold Allodynia
Oxaliplatin is a platinum-based chemotherapeutic agent that causes cold and mechanical allodynia in up to 90% of patients. Silent Nav1.8-positive nociceptive cold sensors have been shown to be unmasked by oxaliplatin, and this event has been causally linked to the development of cold allodynia. We e...
Autores principales: | Iseppon, Federico, Luiz, Ana P., Linley, John E., Wood, John N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998121/ https://www.ncbi.nlm.nih.gov/pubmed/36720644 http://dx.doi.org/10.1523/ENEURO.0395-22.2022 |
Ejemplares similares
-
Silent cold-sensing neurons contribute to cold allodynia in neuropathic pain
por: MacDonald, Donald Iain, et al.
Publicado: (2021) -
Serotonergic mechanism of the relieving effect of bee venom acupuncture on oxaliplatin-induced neuropathic cold allodynia in rats
por: Lee, Ji-Hye, et al.
Publicado: (2014) -
Effect of Bee Venom Acupuncture on Oxaliplatin-Induced Cold Allodynia in Rats
por: Lim, Bong-Soo, et al.
Publicado: (2013) -
Chemogenetic Silencing of Na(V)1.8-Positive Sensory Neurons Reverses Chronic Neuropathic and Bone Cancer Pain in FLEx PSAM(4)-GlyR Mice
por: Haroun, Rayan, et al.
Publicado: (2023) -
Endothelin receptor type A is involved in the development of
oxaliplatin-induced mechanical allodynia and cold allodynia acting through spinal and
peripheral mechanisms in rats
por: Matsuura, Kae, et al.
Publicado: (2021)