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Cloning and Biochemical Characterization of a Hyaluronate Lyase from Bacillus sp. CQMU-D

Hyaluronidase (HAase) can enhance drug diffusion and dissipate edema by degrading hyaluronic acid (HA) in the extracellular matrix into unsaturated HA oligosaccharides in mammalian tissues. Microorganisms are recognized as valuable sources of HAase. In this study, a new hyaluronate lyase (HAaseD) fr...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Liu, Qianqian, Gong, Xue, Jian, Wenwen, Cui, Yihong, Jia, Qianying, Zhang, Jibei, Zhang, Yi, Guo, Yanan, Lu, He, Tu, Zeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Microbiology and Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998204/
https://www.ncbi.nlm.nih.gov/pubmed/36524342
http://dx.doi.org/10.4014/jmb.2209.09036