Disease-specific differences in gene expression, mitochondrial function and mitochondria-endoplasmic reticulum interactions in iPSC-derived cerebral organoids and cortical neurons in schizophrenia and bipolar disorder

We compared transcriptomic profiles of cerebral organoids differentiated from induced pluripotent stem cells of eight schizophrenia and eight bipolar disorder patients to identify genes that were differentially expressed in cerebral organoids between two disorders. Gene ontology analysis showed rela...

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Detalles Bibliográficos
Autores principales: Kathuria, Annie, Lopez-Lengowski, Kara, McPhie, Donna, Cohen, Bruce M., Karmacharya, Rakesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998323/
https://www.ncbi.nlm.nih.gov/pubmed/36915374
http://dx.doi.org/10.1007/s44192-023-00031-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998323/
https://www.ncbi.nlm.nih.gov/pubmed/36915374
http://dx.doi.org/10.1007/s44192-023-00031-8

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