Mucus increases cell iron uptake to impact the release of pro-inflammatory mediators after particle exposure

We tested the hypothesis that (1) mucus production can be included in the cell response to iron deficiency; (2) mucus binds iron and increases cell metal uptake; and subsequently (3) mucus impacts the inflammatory response to particle exposure. Using quantitative PCR, RNA for both MUC5B and MUC5AC i...

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Detalles Bibliográficos
Autores principales: Ghio, Andrew J., Soukup, Joleen M., Dailey, Lisa A., Roggli, Victor L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998431/
https://www.ncbi.nlm.nih.gov/pubmed/36894564
http://dx.doi.org/10.1038/s41598-023-30335-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998431/
https://www.ncbi.nlm.nih.gov/pubmed/36894564
http://dx.doi.org/10.1038/s41598-023-30335-2

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