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Mucus increases cell iron uptake to impact the release of pro-inflammatory mediators after particle exposure
We tested the hypothesis that (1) mucus production can be included in the cell response to iron deficiency; (2) mucus binds iron and increases cell metal uptake; and subsequently (3) mucus impacts the inflammatory response to particle exposure. Using quantitative PCR, RNA for both MUC5B and MUC5AC i...
Autores principales: | Ghio, Andrew J., Soukup, Joleen M., Dailey, Lisa A., Roggli, Victor L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998431/ https://www.ncbi.nlm.nih.gov/pubmed/36894564 http://dx.doi.org/10.1038/s41598-023-30335-2 |
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