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Identification of tumor mutation burden-associated molecular and clinical features in cancer by analyzing multi-omics data

BACKGROUND: Tumor mutation burden (TMB) has been recognized as a predictive biomarker for immunotherapy response in cancer. Systematic identification of molecular features correlated with TMB is significant, although such investigation remains insufficient. METHODS: We analyzed associations of somat...

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Detalles Bibliográficos
Autores principales: Li, Mengyuan, Gao, Xuejiao, Wang, Xiaosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998480/
https://www.ncbi.nlm.nih.gov/pubmed/36911742
http://dx.doi.org/10.3389/fimmu.2023.1090838