Functional selectivity of EM-2 analogs at the mu-opioid receptor

The mu opioid receptor agonists are the most efficacious pain controlling agents but their use is accompanied by severe side effects. More recent developments indicate that some ligands can differentially activate receptor downstream pathways, possibly allowing for dissociation of analgesia mediated...

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Detalles Bibliográficos
Autores principales: Piekielna-Ciesielska, Justyna, Malfacini, Davide, Djeujo, Francine Medjiofack, Marconato, Chantal, Wtorek, Karol, Calo’, Girolamo, Janecka, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998502/
https://www.ncbi.nlm.nih.gov/pubmed/36909169
http://dx.doi.org/10.3389/fphar.2023.1133961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998502/
https://www.ncbi.nlm.nih.gov/pubmed/36909169
http://dx.doi.org/10.3389/fphar.2023.1133961

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