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Patch clamp studies on TRPV4-dependent hemichannel activation in lens epithelium

ATP release from the lens via hemichannels has been explained as a response to TRPV4 activation when the lens is subjected to osmotic swelling. To explore the apparent linkage between TRPV4 activation and connexin hemichannel opening we performed patch-clamp recordings on cultured mouse lens epithel...

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Detalles Bibliográficos
Autores principales: Ek-Vitorin, Jose F., Shahidullah, Mohammad, Lopez Rosales, Joaquin E., Delamere, Nicholas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998544/
https://www.ncbi.nlm.nih.gov/pubmed/36909173
http://dx.doi.org/10.3389/fphar.2023.1101498