Cell surface GRP78 regulates TGFβ1-mediated profibrotic responses via TSP1 in diabetic kidney disease

Introduction: Diabetic kidney disease (DKD) is the leading cause of kidney failure in North America, characterized by glomerular accumulation of extracellular matrix (ECM) proteins. High glucose (HG) induction of glomerular mesangial cell (MC) profibrotic responses plays a central role in its pathog...

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Detalles Bibliográficos
Autores principales: Trink, Jackie, Ahmed, Usman, O’Neil, Kian, Li, Renzhong, Gao, Bo, Krepinsky, Joan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998550/
https://www.ncbi.nlm.nih.gov/pubmed/36909183
http://dx.doi.org/10.3389/fphar.2023.1098321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998550/
https://www.ncbi.nlm.nih.gov/pubmed/36909183
http://dx.doi.org/10.3389/fphar.2023.1098321

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