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Evaluation of the Influence of Sildenafil on the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Vericiguat in Healthy Adults

BACKGROUND AND OBJECTIVE: Vericiguat is approved for the treatment of patients with heart failure with ejection fraction < 45%. Sildenafil, indicated for the treatment of erectile dysfunction, is a potential co-medication in male patients. This study investigated the safety and tolerability of co...

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Detalles Bibliográficos
Autores principales: Boettcher, Michael, Nowotny, Bettina, Krausche, Robert, Becker, Corina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998565/
https://www.ncbi.nlm.nih.gov/pubmed/36729286
http://dx.doi.org/10.1007/s40262-022-01203-5