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The TIMELESS effort for timely DNA replication and protection

Accurate replication of the genome is fundamental to cellular survival and tumor prevention. The DNA replication fork is vulnerable to DNA lesions and damages that impair replisome progression, and improper control over DNA replication stress inevitably causes fork stalling and collapse, a major sou...

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Detalles Bibliográficos
Autores principales: Patel, Jinal A., Kim, Hyungjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998586/
https://www.ncbi.nlm.nih.gov/pubmed/36892674
http://dx.doi.org/10.1007/s00018-023-04738-3