Cargando…

Genome- and transcriptome-wide splicing associations with alcohol use disorder

Genetic mechanisms of alternative mRNA splicing have been shown in the brain for a variety of neuropsychiatric traits, but not substance use disorders. Our study utilized RNA-sequencing data on alcohol use disorder (AUD) in four brain regions (n = 56; ages 40–73; 100% ‘Caucasian’; PFC, NAc, BLA and...

Descripción completa

Detalles Bibliográficos
Autores principales: Huggett, Spencer B., Ikeda, Ami S., Yuan, Qingyue, Benca-Bachman, Chelsie E., Palmer, Rohan H. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9998611/
https://www.ncbi.nlm.nih.gov/pubmed/36894673
http://dx.doi.org/10.1038/s41598-023-30926-z